Modeling pacemaker deterioration with age
نویسندگان
چکیده
منابع مشابه
Modeling pacemaker deterioration with age
New JGP study models how sinoatrial node pacemaker activity changes in aged hearts.
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Age-related deterioration of pacemaker function has been documented in mammals, including humans. In aged isolated sinoatrial node tissues and cells, reduction in the spontaneous action potential (AP) firing rate was associated with deterioration of intracellular and membrane mechanisms; however, their relative contribution to age-associated deficient pacemaker function is not known. Interestin...
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ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 2017
ISSN: 0022-1295,1540-7748
DOI: 10.1085/jgp.201711869